On 31 December 1991 – the recognition of Ukraine by the Grand Duchy of Luxembourg,
On 1 July 1992 - the establishment of diplomatic relations between the Grand Duchy of Luxembourg and Ukraine.
The highest level political contacts started with the visit of the President of Ukraine Leonid Kravchuk to Luxembourg on 14 June 1994 during which the Partnership and Cooperation Agreement between Ukraine and the European Communities and their Member States, the Joint Declaration of the President of Ukraine and the Prime Minister of Luxembourg, the Agreement between the Government of Ukraine and the Government of the Grand Duchy of Luxembourg on Air Transport were signed.
In 1995 - Mr. Claude Radoux is appointed Honorary Consul of Ukraine.
On 2 December 1996 - The President of Ukraine Leonid Kuchma met with the Prime Minister of Luxembourg J.-C.Juncker within the framework of the OSCE summit in Lisbon.
In September 1997 and June 1998- the Prime Ministers of two states exchanged visits.
On 26 June 2001 - Prime Minister of Ukraine Anatoliy Kinakh met with his Luxembourg counterpart J.-C.Juncker during the 4th meeting of the Cooperation Council Ukraine-EU.
The Head of the Luxembourg Government has repeatedly expressed his strong political support for European and Euro-Atlantic integration during Ukraine.
Thanks to its support during the Luxembourg Presidency of the European Union (second mid of 1997) et sa participation à la Troïka de l’UE a été prise la décision de lancer le premier Sommet l’Ukraine-l’UE (Kyiv, le 5 septembre 1997) et la première réunion du Conseil de coopération l’Ukraine-l’UE (Luxembourg, June 1998).
In November 1994 and in September 1996, 1997, 1999 in New York - there were meetings of foreign ministers during which they discussed issues of international and European security, multilateral and bilateral cooperation.
In 2000 the volume of trade increased by 65 per cent compared to 1999 and reached $11.7 million, including Ukrainian exports of $2.6 million and imports of $9.1 million.
In 2001 trade increased by 20% compared to the previous year and reached $14.1 million with a negative balance for Ukraine of $12.3 million.
The volume of Luxembourg investments in the Ukrainian economy was also up in 2001 (44%) and reached $14.4m.
Within the framework of charitable activities, the Luxembourg Red Cross carried out a programme of assistance to children with heart diseases. In 1992-1997 more than 100 Ukrainian children were diagnosed and operated on, spending more than $1 million on this project. The programme of support and assistance to cardiac surgery continues to be carried out at the Interregional Centre of Cardiac Surgery in Lviv.